DMBT1 抗体 (N-Term)
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- 抗原 See all DMBT1 抗体
- DMBT1 (Deleted in Malignant Brain Tumors 1 (DMBT1))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DMBT1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- DMBT1 antibody was raised against the N terminal of DMBT1
- 纯化方法
- Affinity purified
- 免疫原
- DMBT1 antibody was raised using the N terminal of DMBT1 corresponding to a region with amino acids SWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWG
- Top Product
- Discover our top product DMBT1 Primary Antibody
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- 应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. - 说明
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DMBT1 Blocking Peptide, catalog no. 33R-8945, is also available for use as a blocking control in assays to test for specificity of this DMBT1 antibody
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of DMBT1 antibody in PBS
- 浓度
- Lot specific
- 缓冲液
- PBS
- 注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- 抗原
- DMBT1 (Deleted in Malignant Brain Tumors 1 (DMBT1))
- 别名
- DMBT1 (DMBT1 产品)
- 别名
- GP340 antibody, muclin antibody, CRP antibody, CRP-[a] antibody, CRP-[b] antibody, Crpd antibody, DBMT1 antibody, gp300 antibody, p80 antibody, DMBT1 antibody, gp340 antibody, deleted in malignant brain tumors 1 antibody, deleted in malignant brain tumors 1 protein antibody, gp340 antibody, deleted in malignant brain tumors 1 S homeolog antibody, DMBT1 antibody, Dmbt1 antibody, LOC100064515 antibody, dmbt1 antibody, ST201phi2-1p340 antibody, dmbt1.S antibody
- 背景
- Loss of sequences from human chromosome 10q has been associated with the progression of human cancers. The gene DMBT1 was originally isolated based on its deletion in a medulloblastoma cell line. DMBT1 is expressed with transcripts of 6.0, 7.5, and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung, although the 7.5 kb transcript has not been characterized. The DMBT1 protein is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID). Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition. This indicates that DMBT1 may not be a classical tumor supressor gene, but rather play a role in the interaction of tumor cells and the immune system.
- 分子量
- 258 kDa (MW of target protein)
- 途径
- Activation of Innate immune Response
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