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GALE 抗体 (N-Term)

GALE 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN631451
发货至: 中国
  • 抗原 See all GALE 抗体
    GALE (UDP-Galactose-4-Epimerase (GALE))
    抗原表位
    • 15
    • 8
    • 7
    • 2
    • 2
    • 1
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    • 1
    N-Term
    适用
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    宿主
    • 46
    • 4
    克隆类型
    • 48
    • 2
    多克隆
    标记
    • 21
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    • 1
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    This GALE antibody is un-conjugated
    应用范围
    • 39
    • 15
    • 13
    • 13
    • 5
    • 5
    • 5
    • 3
    • 1
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    Western Blotting (WB)
    特异性
    GALE antibody was raised against the N terminal of GALE
    纯化方法
    Affinity purified
    免疫原
    GALE antibody was raised using the N terminal of GALE corresponding to a region with amino acids AEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRR
    Top Product
    Discover our top product GALE Primary Antibody
  • 应用备注
    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.
    说明

    GALE Blocking Peptide, catalog no. 33R-1135, is also available for use as a blocking control in assays to test for specificity of this GALE antibody

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of GALE antibody in PBS
    浓度
    Lot specific
    缓冲液
    PBS
    注意事项
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原
    GALE (UDP-Galactose-4-Epimerase (GALE))
    别名
    GALE (GALE 产品)
    背景
    GALE is an UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation.
    分子量
    38 kDa (MW of target protein)
    途径
    Response to Water Deprivation, Cellular Glucan Metabolic Process
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