HAAO 抗体 (N-Term)
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- 抗原 See all HAAO 抗体
- HAAO (3-hydroxyanthranilate 3,4-Dioxygenase (HAAO))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HAAO antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- HAAO antibody was raised against the N terminal of HAAO
- 纯化方法
- Affinity purified
- 免疫原
- HAAO antibody was raised using the N terminal of HAAO corresponding to a region with amino acids HRDVVIRQGEIFLLPARVPHSPQRFANTVGLVVERRRLETELDGLRYYVG
- Top Product
- Discover our top product HAAO Primary Antibody
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- 应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. - 说明
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HAAO Blocking Peptide, catalog no. 33R-3836, is also available for use as a blocking control in assays to test for specificity of this HAAO antibody
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of HAAO antibody in PBS
- 浓度
- Lot specific
- 缓冲液
- PBS
- 注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- 抗原
- HAAO (3-hydroxyanthranilate 3,4-Dioxygenase (HAAO))
- 别名
- HAAO (HAAO 产品)
- 别名
- Afu2g17450 antibody, 0610007K21Rik antibody, 0610012J07Rik antibody, 3-HAO antibody, 3-HAOxase antibody, 3HAO antibody, zgc:103585 antibody, HAO antibody, 3-hydroxyanthranilate 3,4-dioxygenase antibody, 3-hydroxyanthranilate 3,4-dioxygenase L homeolog antibody, SPO1774 antibody, CNB05620 antibody, AFUA_2G17450 antibody, Bcep18194_C7641 antibody, Kfla_5491 antibody, Micau_4935 antibody, RBRH_03005 antibody, Krodi_1278 antibody, haao antibody, HAAO antibody, Haao antibody, haao.L antibody
- 背景
- 3-Hydroxyanthranilate 3,4-dioxygenase is a monomeric cytosolic protein belonging to the family of intramolecular dioxygenases containing nonheme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney, and is also present in low amounts in the central nervous system. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurologic and inflammatory disorders.
- 分子量
- 32 kDa (MW of target protein)
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