Arrestin 3 抗体 (Middle Region)
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- 抗原 See all Arrestin 3 (ARRB2) 抗体
- Arrestin 3 (ARRB2) (Arrestin, beta 2 (ARRB2))
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抗原表位
- Middle Region
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适用
- 人, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Arrestin 3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 特异性
- Arrestin B2 antibody was raised against the middle region of ARRB2
- 纯化方法
- Affinity purified
- 免疫原
- Arrestin B2 antibody was raised using the middle region of ARRB2 corresponding to a region with amino acids RLVIRKVQFAPEKPGPQPSAETTRHFLMSDRSLHLEASLDKELYYHGEPL
- Top Product
- Discover our top product ARRB2 Primary Antibody
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- 应用备注
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WB: 1 µg/mL, IHC: 4-8 µg/mL
Optimal conditions should be determined by the investigator. - 说明
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Arrestin B2 Blocking Peptide, catalog no. 33R-8056, is also available for use as a blocking control in assays to test for specificity of this Arrestin B2 antibody
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of ARRB2 antibody in PBS
- 浓度
- Lot specific
- 缓冲液
- PBS
- 注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- 抗原
- Arrestin 3 (ARRB2) (Arrestin, beta 2 (ARRB2))
- Abstract
- ARRB2 产品
- 别名
- ARRB2 antibody, arb2 antibody, arr2 antibody, arrestin antibody, barr2 antibody, betaarr2 antibody, ARB2 antibody, ARR2 antibody, BARR2 antibody, BARRES antibody, AI326910 antibody, AW122872 antibody, arrb2 antibody, zgc:64007 antibody, arrestin beta 2 antibody, arrestin, beta 2 antibody, arrestin beta 2 L homeolog antibody, arrestin, beta 2b antibody, ARRB2 antibody, arrb2 antibody, Arrb2 antibody, arrb2.L antibody, arrb2b antibody
- 背景
- Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. ARRB2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors.
- 分子量
- 44 kDa (MW of target protein)
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Phototransduction, Thromboxane A2 Receptor Signaling
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