PCMT1 抗体
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- 抗原 See all PCMT1 抗体
- PCMT1 (Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PCMT1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- Purified
- 免疫原
- PCMT1 antibody was raised using a synthetic peptide corresponding to a region with amino acids APYDAIHVGAAAPVVPQALIDQLKPGGRLILPVGPAGGNQMLEQYDKLQD
- Top Product
- Discover our top product PCMT1 Primary Antibody
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- 应用备注
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WB: 2.5 µg/mL
Optimal conditions should be determined by the investigator. - 说明
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PCMT1 Blocking Peptide, catalog no. 33R-1442, is also available for use as a blocking control in assays to test for specificity of this PCMT1 antibody
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of PCMT1 antibody in PBS
- 浓度
- Lot specific
- 缓冲液
- PBS
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- 抗原
- PCMT1 (Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1))
- 别名
- PCMT1 (PCMT1 产品)
- 别名
- PIMT antibody, C79501 antibody, PCM antibody, PCMT antibody, etID309741.20 antibody, fj13d06 antibody, pimt antibody, wu:fj13d06 antibody, protein-L-isoaspartate (D-aspartate) O-methyltransferase antibody, protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 antibody, protein-L-isoaspartate (D-aspartate) O-methyltransferase L homeolog antibody, protein-L-isoaspartate(D-aspartate)O-methyltransferase antibody, PCMT1 antibody, Pcmt1 antibody, pcmt1.L antibody, pcmt1 antibody, pcmt antibody
- 背景
- Three classes of protein carboxyl methyltransferases, distinguished by their methyl-acceptor substrate specificity, have been found in prokaryotic and eukaryotic cells. The type II enzyme catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to the free carboxyl groups of D-aspartyl and L-isoaspartyl residues. These methyl-accepting residues result from the spontaneous deamidation, isomerization, and racemization of normal L-aspartyl and L-asparaginyl residues and represent sites of covalent damage to aging proteins PCMT1 (EC 2.1.1.77) is a protein repair enzyme that initiates the conversion of abnormal D-aspartyl and L-isoaspartyl residues to the normal L-aspartyl form.
- 分子量
- 25 kDa (MW of target protein)
- 途径
- Ribonucleoprotein Complex Subunit Organization
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