SFPQ 抗体
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- 抗原 See all SFPQ 抗体
- SFPQ (Splicing Factor Proline/glutamine-Ric (SFPQ))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SFPQ antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 纯化方法
- Purified
- 免疫原
- SFPQ antibody was raised using a synthetic peptide corresponding to a region with amino acids PVIVEPLEQLDDEDGLPEKLAQKNPMYQKERETPPRFAQHGTFEYEYSQR
- Top Product
- Discover our top product SFPQ Primary Antibody
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- 应用备注
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WB: 5 µg/mL, IHC: 4-8 µg/mL
Optimal conditions should be determined by the investigator. - 说明
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SFPQ Blocking Peptide, catalog no. 33R-7413, is also available for use as a blocking control in assays to test for specificity of this SFPQ antibody
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of SFPQ antibody in PBS
- 浓度
- Lot specific
- 缓冲液
- PBS
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- 抗原
- SFPQ (Splicing Factor Proline/glutamine-Ric (SFPQ))
- 别名
- SFPQ (SFPQ 产品)
- 别名
- 1110004P21Rik antibody, 2810416M14Rik antibody, 5730453G22Rik antibody, 9030402K04Rik antibody, AU021830 antibody, D4Ertd314e antibody, Gm12940 antibody, OTTMUSG00000009329 antibody, PSF antibody, REP1 antibody, hm:zeh0027 antibody, wu:fa11h12 antibody, wu:fd10f03 antibody, zgc:85935 antibody, POMP100 antibody, splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) antibody, splicing factor proline/glutamine-rich antibody, splicing factor proline and glutamine rich antibody, Sfpq antibody, sfpq antibody, SFPQ antibody
- 背景
- SFPQ is DNA- and RNA binding protein. It is essential pre-mRNA splicing factor required early in spliceosome formation and for splicing catalytic step II, probably as an heteromer with NONO. It binds to pre-mRNA in spliceosome C complex, and specifically binds to intronic polypyrimidine tracts. It interacts with U5 snRNA. It may be involved in a pre-mRNA coupled splicing and polyadenylation process as component of a snRNP-free complex with SNRPA/U1A. SFPQ may be involved in homologous DNA pairing. SFPQ is involved in transcriptional regulation. It binds the DNA sequence 5'-CTGAGTC-3' in the insulin-like growth factor response element (IGFRE) and inhibits IGF-I-stimulated transcriptional activity.
- 分子量
- 78 kDa (MW of target protein)
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