PAWR 抗体
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- 抗原 See all PAWR 抗体
- PAWR (PRKC, Apoptosis, WT1, Regulator (PAWR))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PAWR antibody is un-conjugated
- 应用范围
- 请咨询
- 原理
- Rabbit Anti-Prostate Apoptosis Response protein-4 Antibody,
- Top Product
- Discover our top product PAWR Primary Antibody
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- 限制
- 仅限研究用
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- 储存条件
- 4 °C,-20 °C
- 储存方法
- 2-8°C (short-term), -20°C (long-term)
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- 抗原
- PAWR (PRKC, Apoptosis, WT1, Regulator (PAWR))
- 别名
- Prostate Apoptosis Response protein-4 (PAWR 产品)
- 别名
- MGC81382 antibody, pawrl antibody, zgc:103513 antibody, PAWR antibody, PAR4 antibody, Par-4 antibody, Par4 antibody, 2310001G03Rik antibody, pro-apoptotic WT1 regulator antibody, PRKC, apoptosis, WT1, regulator L homeolog antibody, PRKC, apoptosis, WT1, regulator antibody, PAWR antibody, pawr.L antibody, pawr antibody, Pawr antibody
- 背景
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Target Description: Pro-apoptopic protein capable of selectively inducing apoptosis in cancer cells, sensitizing the cells to diverse apoptotic stimuli and causing regression of tumors in animal models. Induces apoptosis in certain cancer cells by activation of the Fas prodeath pathway and coparallel inhibition of NF-kappa-B transcriptional activity. Inhibits the transcriptional activation and augments the transcriptional repression mediated by WT1. Down- regulates the anti-apoptotic protein BCL2 via its interaction with WT1. Seems also to be a transcriptional repressor by itself. May be directly involved in regulating the amyloid precursor protein (APP) cleavage activity of BACE1.
Gene Symbol: PAWR
- 基因ID
- 5074
- UniProt
- Q96IZ0
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