PGC 抗体 (Biotin)
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- 抗原 See all PGC 抗体
- PGC (Pepsinogen C (PGC))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PGC antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), ELISA
- 原理
- Mouse anti-Human PGC Biotinylated Antibody
- 免疫原
- This antibody was produced by fusion of mouse myeloma with B cells obtained from a mouse immunized with a recombinant protein immunogen. The IgG fraction of tissue culture supernatant was purified by Protein G/A affinity chromatography.
- 克隆位点
- 4H4-E9-E4
- 亚型
- IgG1
- Top Product
- Discover our top product PGC Primary Antibody
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- 应用备注
- ELISA (recommended dilution= 1:320,000), Western Blotting (recommended dilution= 1:1,000-5,000)
- 限制
- 仅限研究用
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- 溶解方式
- A separate vial of dilution buffer is provided for reconstitution. The antibody is supplied lyophilized, originally containing PBS, without preservative stabilizers (e. g. sodium azide). The final amount is indicated on the shipping vial.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- -20°C
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- 抗原
- PGC (Pepsinogen C (PGC))
- 别名
- PGC (PGC 产品)
- 别名
- PEPC antibody, PGII antibody, 2210410L06Rik antibody, Upg-1 antibody, Upg1 antibody, CPGC antibody, gastricsin antibody, PG1 antibody, Pg-1 antibody, PGNC antibody, PGC antibody, Gastricsin antibody, progastricsin (pepsinogen C) antibody, progastricsin antibody, PGC antibody, Pgc antibody
- 背景
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Target Description: PGC gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1.
- UniProt
- P20142
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