CD63 抗体
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- 抗原 See all CD63 抗体
- CD63
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD63 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC)
- 原理
- Mouse anti-Human CD63 Antibody Cocktail [IHC only]
- 特异性
- Cytoplasmic
- 纯化方法
- The smooth plasma membrane fraction of MeWo cells (NKI/C3) and recombinant human full-length protein (LAMP3/968) were used as the immunogen for the CD63 antibody cocktail.
- 免疫原
- The smooth plasma membrane fraction of MeWo cells (NKI/C3) and recombinant human full-length protein (LAMP3/968) were used as the immunogen for the CD63 antibody cocktail.
- Top Product
- Discover our top product CD63 Primary Antibody
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- 应用备注
- Prediluted format : incubate for 30 min at RT (2)
- 限制
- 仅限研究用
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- 缓冲液
- Prediluted in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- 抗原
- CD63
- 别名
- CD63 antigen (CD63 产品)
- 别名
- C75951 antibody, ME491 antibody, Tspan30 antibody, LAMP-3 antibody, MLA1 antibody, OMA81H antibody, TSPAN30 antibody, TSP29FA antibody, CD63 antigen antibody, CD63 molecule antibody, Cd63 molecule antibody, Cd63 antibody, CD63 antibody
- 背景
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Target Description: This mAb recognizes protein of 26 kDa-60 kDa, which is identified as CD63. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.
Gene Symbol: CD63///MLA1///TSPAN30
- 基因ID
- 967
- UniProt
- P08962
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