CA9 抗体
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- 抗原 See all CA9 抗体
- CA9 (Carbonic Anhydrase IX (CA9))
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适用
- 人, 马
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CA9 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
- 原理
- Mouse anti-Human/Horse CAIX Antibody Carbonic Anhydrase IX [Sodium Azide Free]
- 特异性
- Cell surface and cytoplasmic
- 纯化方法
- The microsomal fraction of human renal cortical tissue homogenate was used as the immunogen for this Carbonic Anhydrase IX / CAIX antibody.
- 免疫原
- The microsomal fraction of human renal cortical tissue homogenate was used as the immunogen for this Carbonic Anhydrase IX / CAIX antibody.
- Top Product
- Discover our top product CA9 Primary Antibody
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- 应用备注
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FACS: 0.5-1 μg/million cells
IF: 1-2 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2) - 限制
- 仅限研究用
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- 缓冲液
- In 1X PBS ( pH 7.4), BSA free, sodium azide free
- 储存液
- Azide free
- 储存条件
- 4 °C,-20 °C
- 储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- 抗原
- CA9 (Carbonic Anhydrase IX (CA9))
- 别名
- Carbonic anhydrase 9 (CA9 产品)
- 别名
- CA9 antibody, CAIX antibody, Ca9 antibody, MN/CA9 antibody, MN antibody, carbonic anhydrase 9 antibody, CA9 antibody, CAH9 antibody, Car9 antibody
- 背景
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Target Description: This antibody recognizes a glycoprotein of ~200 kDa, identified as renal cell carcinoma protein, carbonic anhydrase IX / CAIX, or gp200. Its epitope resides in the carbohydrate domain of the protein. The CAIX antibody shows no significant cross-reactivity with other carbohydrate determinants, such as the Lewis blood group antigens, epithelial membrane antigen, HMFG, and AB blood group antigens. In normal kidney, CAIX is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Reportedly, it is expressed by 93 % of primary and 84 % of metastatic renal cell carcinomas. This CAIX antibody may be useful in the investigations of carcinomas of proximal nephrogenic differentiation, especially those showing tubular differentiation.
Gene Symbol: CA9///G250///MN
- 基因ID
- 768
- UniProt
- Q16790
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