TYR 抗体
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- 抗原 See all TYR 抗体
- TYR (Tyrosinase (TYR))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TYR antibody is un-conjugated
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应用范围
- Immunofluorescence (IF), Immunohistochemistry (IHC), Flow Cytometry (FACS)
- 原理
- Mouse anti-Human Tyrosinase Antibody [Sodium Azide Free]
- 特异性
- Cytoplasmic
- 纯化方法
- Recombinant tyrosinase protein was used as the immunogen for this Tyrosinase antibody.
- 免疫原
- Recombinant tyrosinase protein was used as the immunogen for this Tyrosinase antibody.
- Top Product
- Discover our top product TYR Primary Antibody
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- 应用备注
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Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2) - 限制
- 仅限研究用
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- 缓冲液
- In 1X PBS, BSA free, sodium azide free
- 储存液
- Azide free
- 储存条件
- 4 °C,-20 °C
- 储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- 抗原
- TYR (Tyrosinase (TYR))
- 别名
- Tyrosinase (TYR 产品)
- 别名
- sandy antibody, zgc:109705 antibody, TYR antibody, TYRO antibody, tyr antibody, LOC100136546 antibody, CMM8 antibody, OCA1A antibody, OCAIA antibody, SHEP3 antibody, albino antibody, c antibody, skc35 antibody, C antibody, tyrosinase antibody, TYRosinase antibody, tyrosinase S homeolog antibody, tyr antibody, tyr-5 antibody, tyr.S antibody, TYR antibody, Celal_3121 antibody, Halhy_4121 antibody, Mesop_2736 antibody, LOC100136546 antibody, Tyr antibody
- 背景
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Target Description: Recognizes a cluster of proteins between 70-80 kDa, identified as tyrosinase. Occasionally a minor band at 55 kDa is also detected. This mAb shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway, the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Staining of melanomas with this mAb shows tyrosinase in melanotic as well as amelanotic variants. This mAb is a useful marker for melanocytes and melanomas.
Gene Symbol: TYR
- 基因ID
- 7299
- UniProt
- P14679
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