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IGKV1D-16 抗体

IGKV1D-16 适用: 人 IHC, FACS, WB, IF 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN6296346
发货至: 中国
  • 抗原 See all IGKV1D-16 products
    IGKV1D-16 (Immunoglobulin kappa Variable 1D-16 (IGKV1D-16))
    适用
    宿主
    • 1
    小鼠
    克隆类型
    • 1
    单克隆
    标记
    • 1
    This IGKV1D-16 antibody is un-conjugated
    应用范围
    Immunohistochemistry (IHC), Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF)
    原理
    Mouse anti-Human Kappa Light Chain Antibody [Sodium Azide Free]
    特异性
    Cell surface, cytoplasmic and secreted
    纯化方法
    Human B-Lymphoma Cells were used as the immunogen for this Kappa light chain antibody.
    免疫原
    Human B-Lymphoma Cells were used as the immunogen for this Kappa light chain antibody.
  • 应用备注
    FACS: 0.5-2.0 μg/million cells
    IF: 1-2 μg/mL
    WB: 0.5-1 μg/mL
    IHC (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
    Prediluted format: incubate for 30 min at RT (2)
    限制
    仅限研究用
  • 缓冲液
    In 1X PBS ( pH 7.4), BSA free, sodium azide free
    储存液
    Azide free
    储存条件
    4 °C,-20 °C
    储存方法
    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原
    IGKV1D-16 (Immunoglobulin kappa Variable 1D-16 (IGKV1D-16))
    别名
    Immunoglobulin kappa variable 1D-16 (IGKV1D-16 产品)
    别名
    IGKV1D16 antibody, L15 antibody, L15a antibody, immunoglobulin kappa variable 1D-16 antibody, IGKV1D-16 antibody
    背景

    Target Description: This antibody is specific to the kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. In general, the ratio of Kappa to Lambda is 3:1. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

    Gene Symbol: IGKV1D-16///IGKC

    基因ID
    3514
    UniProt
    P01601, P01834
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