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RNMT 抗体

RNMT 适用: 人, 大鼠, Cow, 犬 IHC, IF, FACS 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN6296036
发货至: 中国
  • 抗原 See all RNMT 抗体
    RNMT (RNA Guanine-7 Methyltransferase (RNMT))
    适用
    • 11
    • 7
    • 7
    • 7
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    人, 大鼠, Cow, 犬
    宿主
    • 6
    • 5
    小鼠
    克隆类型
    • 6
    • 5
    单克隆
    标记
    • 11
    This RNMT antibody is un-conjugated
    应用范围
    • 8
    • 6
    • 5
    • 3
    • 2
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
    原理
    Mouse anti-Human/Cow/Dog/Rat TAG-72 Antibody Cocktail [Sodium Azide Free]
    特异性
    Cytoplasmic and cell surface
    纯化方法
    A membrane-enriched fraction of a human breast carcinoma liver metastasis (B72.3) and purified TAG-72 protein (CC49) were used as the immunogens for this TAG-72 antibody cocktail.
    免疫原
    A membrane-enriched fraction of a human breast carcinoma liver metastasis (B72.3) and purified TAG-72 protein (CC49) were used as the immunogens for this TAG-72 antibody cocktail.
    Top Product
    Discover our top product RNMT Primary Antibody
  • 应用备注
    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 1-2 μg/mL
    Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
    限制
    仅限研究用
  • 缓冲液
    In 1X PBS, BSA free, sodium azide free
    储存液
    Azide free
    储存条件
    4 °C,-20 °C
    储存方法
    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原
    RNMT (RNA Guanine-7 Methyltransferase (RNMT))
    别名
    mRNA cap guanine-N7 methyltransferase   (RNMT 产品)
    别名
    xCMT1 antibody, MET antibody, RG7MT1 antibody, hCMT1c antibody, 2610002P10Rik antibody, AI848273 antibody, Rg7mt1 antibody, mKIAA0398 antibody, rnmt antibody, im:6910566 antibody, wu:fi09c12 antibody, RNA (guanine-7-) methyltransferase L homeolog antibody, RNA guanine-7 methyltransferase antibody, RNA (guanine-7-) methyltransferase antibody, rnmt.L antibody, RNMT antibody, Rnmt antibody, rnmt antibody
    背景

    Target Description: Recognizes an oncofetal antigen of 220 kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This mAb defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80 % sensitivity and 93 % specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.

    Gene Symbol: tag-72  C25A1.3

    基因ID
    182875
    UniProt
    Q9XVS1
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