SKIL 抗体
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- 抗原 See all SKIL 抗体
- SKIL (SKI-Like Oncogene (SKIL))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SKIL antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein of human SKIL
- 亚型
- IgG
- Top Product
- Discover our top product SKIL Primary Antibody
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- 应用备注
- WB 1:500 - 1:2000
- 说明
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Isoform SNON and isoform SNOA are widely expressed, Highest expression is found in skeletal muscle, followed by placenta and lung, Lowest expression in heart, brain and pancreas, Isoform SNOI expression is restricted to skeletal muscle
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20C. Avoid freeze / thaw cycles.
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- 抗原
- SKIL (SKI-Like Oncogene (SKIL))
- 别名
- SKIL (SKIL 产品)
- 别名
- SNO antibody, SnoA antibody, SnoI antibody, SnoN antibody, Skir antibody, Sno antibody, SKIL antibody, DKFZp459L122 antibody, sno antibody, zgc:193698 antibody, SKI like proto-oncogene antibody, SKI-like proto-oncogene antibody, ski-like protein antibody, SKI-like antibody, SKI-like proto-oncogene b antibody, SKIL antibody, Skil antibody, LOC100010058 antibody, skil antibody, skilb antibody
- 背景
- The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene.
- 分子量
- 76.976 kDa
- 基因ID
- 6498
- UniProt
- P12757
- 途径
- Positive Regulation of Response to DNA Damage Stimulus
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