S100A12 抗体
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- 抗原 See all S100A12 抗体
- S100A12 (S100 Calcium Binding Protein A12 (S100A12))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This S100A12 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC)
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein of human S100A12
- 亚型
- IgG
- Top Product
- Discover our top product S100A12 Primary Antibody
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- 应用备注
- IHC 1:50 - 1:100
- 说明
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Predominantly expressed by neutrophils, monocytes and activated macrophages, Expressed by eosinophils and macrophages in asthmatic airways in regions where mast cells accumulate, Found in high concentrations in the serum of patients suffering from various inflammatory disorders, such as rheumatoid arthritis, psoriatic arthritis, Crohn's disease, ulcerative colitis, and Kawasaki disease
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20C. Avoid freeze / thaw cycles.
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- 抗原
- S100A12 (S100 Calcium Binding Protein A12 (S100A12))
- 别名
- S100A12 (S100A12 产品)
- 别名
- CAAF1 antibody, CAGC antibody, CGRP antibody, ENRAGE antibody, MRP-6 antibody, MRP6 antibody, p6 antibody, CO-AG antibody, EN-RAGE antibody, S100 calcium binding protein A12 antibody, protein S100-A12 antibody, S100A12 antibody, LOC101103771 antibody
- 背景
- The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. The protein includes an antimicrobial peptide which has antibacterial activity.
- 分子量
- 10.575 kDa
- 基因ID
- 6283
- UniProt
- P80511
- 途径
- Toll-Like Receptors Cascades, S100 Proteins
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