PEG3 抗体
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- 抗原 See all PEG3 抗体
- PEG3 (Paternally Expressed 3 (PEG3))
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PEG3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein of human PEG3
- 亚型
- IgG
- Top Product
- Discover our top product PEG3 Primary Antibody
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- 应用备注
- WB 1:500 - 1:2000
- 说明
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Brain, glial cells, astrocytes, embryo, placenta, testis, ovary and uterus, In the placenta it is found in the layer of villous cytotrophoblast cells while in the ovary it is found in the cells of the ovarian stroma including the thecal layers around the follicles, Expression is highly repressed in glioma cell lines
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20C. Avoid freeze / thaw cycles.
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- 抗原
- PEG3 (Paternally Expressed 3 (PEG3))
- 别名
- PEG3 (PEG3 产品)
- 别名
- PW1 antibody, ZKSCAN22 antibody, ZNF904 antibody, ZSCAN24 antibody, AL022617 antibody, ASF-1 antibody, End4 antibody, Gcap4 antibody, Pw1 antibody, Zfp102 antibody, mKIAA0287 antibody, PEG3 antibody, paternally expressed 3 antibody, paternally-expressed gene 3 protein antibody, PEG3 antibody, Peg3 antibody, LOC100448879 antibody
- 背景
- In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5' exons and a common promoter and both genes are paternally expressed (PMID:15203203). Alternative splicing events connect their shared 5' exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons. Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis. PEG3 has also shown tumor suppressor activity and tumorigenesis in glioma and ovarian cells. Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms.
- 分子量
- 180.827 kDa
- 基因ID
- 5178
- UniProt
- Q9GZU2
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