YWHAB/YWHAZ 抗体 (pSer184, pSer186)
YWHAB/YWHAZ
适用: 人, 小鼠, 大鼠
WB, ELISA
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all YWHAB/YWHAZ products
- YWHAB/YWHAZ (14-3-3 beta/zeta (YWHAB/YWHAZ))
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抗原表位
- AA 120-200, pSer184, pSer186
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This YWHAB/YWHAZ antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 原理
- 14-3-3 β/ζ is a protein encoded by the YWHAZ gene which is approximately 27,7 kDa. 14-3-3 β/ζ is localised to the cytoplasm and melanosome. It is involved in the activation of cAMP-dependent PKA, development slit-robo signalling and activation of BH3-only proteins. It is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signalling pathways. It binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. 14-3-3 β/ζ is expressed in the nervous system, intestine, skin, blood and eye. STJ90562 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This primary antibody specifically binds to endogenous 14-3-3 β/ζ protein which only binds about S184/186 when S184/186 is phosphorylated.
- 特异性
- Phospho-14-3-3 β/ζ (S184/186) Polyclonal Antibody detects endogenous levels of 14-3-3 β/ζ protein only when phosphorylated at S184/186.
- 产品特性
- Rabbit polyclonal to Phospho-14-3-3 β/ζ (S184/186).
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized peptide derived from human 14-3-3 beta/zeta around the phosphorylation site of S184/186.
- 亚型
- IgG
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- 应用备注
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WB 1:500-1:2000
ELISA 1:5000 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- 抗原
- YWHAB/YWHAZ (14-3-3 beta/zeta (YWHAB/YWHAZ))
- 别名
- 14-3-3 beta/zeta (YWHAB/YWHAZ 产品)
- 别名
- 14-3-3z antibody, 14-3-3zeta antibody, kcip-1 antibody, ywhaq antibody, Ywhaz antibody, ACYPI003154 antibody, 1433z antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta antibody, 14-3-3 protein zeta antibody, ywhaz antibody, 14-3-3zeta antibody, YWHAZ antibody, 1433z antibody
- 分子量
- 28 kDa
- 基因ID
- 7534
- UniProt
- P63104
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