TRIM63 抗体 (N-Term)
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- 抗原 See all TRIM63 抗体
- TRIM63 (Tripartite Motif Containing 63 (TRIM63))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TRIM63 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- TRIM63 Antibody detects endogenous levels of total TRIM63.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human TRIM63, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product TRIM63 Primary Antibody
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:100, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- TRIM63 (Tripartite Motif Containing 63 (TRIM63))
- 别名
- TRIM63 (TRIM63 产品)
- 别名
- IRF antibody, MURF1 antibody, MURF2 antibody, RNF28 antibody, SMRZ antibody, Murf antibody, Murf1 antibody, Rnf28 antibody, MuRF1 antibody, RF1 antibody, rnf30 antibody, MGC80210 antibody, TRIM63 antibody, MuRF antibody, fc50c07 antibody, trim63 antibody, wu:fc50c07 antibody, zgc:86757 antibody, tripartite motif containing 63 antibody, tripartite motif-containing 63 antibody, tripartite motif containing 63 S homeolog antibody, tripartite motif containing 63a antibody, TRIM63 antibody, Trim63 antibody, trim63.S antibody, trim63a antibody
- 背景
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Description: E3 ubiquitin ligase. Mediates the ubiquitination and subsequent proteasomal degradation of CKM, GMEB1 and HIBADH. Regulates the proteasomal degradation of muscle proteins under amino acid starvation, where muscle protein is catabolized to provide other organs with amino acids. Inhibits de novo skeletal muscle protein synthesis under amino acid starvation. Regulates proteasomal degradation of cardiac troponin I/TNNI3 and probably of other sarcomeric-associated proteins. May play a role in striated muscle atrophy and hypertrophy by regulating an anti-hypertrophic PKC-mediated signaling pathway. May regulate the organization of myofibrils through TTN in muscle cells.
Gene: TRIM63
- 分子量
- 40kDa
- 基因ID
- 84676
- UniProt
- Q969Q1
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