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ZNRF1 抗体 (Internal Region)

ZNRF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6266142
发货至: 中国
  • 抗原 See all ZNRF1 抗体
    ZNRF1 (Zinc and Ring Finger Protein 1 (ZNRF1))
    抗原表位
    • 7
    • 7
    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 45
    • 26
    • 18
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 40
    • 4
    • 1
    克隆类型
    • 43
    • 2
    多克隆
    标记
    • 15
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ZNRF1 antibody is un-conjugated
    应用范围
    • 24
    • 16
    • 13
    • 5
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    特异性
    ZNRF1 Antibody detects endogenous levels of total ZNRF1.
    预测反应
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human ZNRF1, corresponding to a region within the internal amino acids.
    亚型
    IgG
  • 应用备注
    WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    ZNRF1 (Zinc and Ring Finger Protein 1 (ZNRF1))
    别名
    ZNRF1 (ZNRF1 产品)
    别名
    NIN283 antibody, B830022L21Rik antibody, Rnf42 antibody, Zrfp1 antibody, nin283 antibody, zgc:77896 antibody, zrfp1 antibody, zinc and ring finger 1 antibody, zinc and ring finger 1, E3 ubiquitin protein ligase S homeolog antibody, ZNRF1 antibody, Znrf1 antibody, znrf1 antibody, znrf1.S antibody
    背景

    Description: E3 ubiquitin-protein ligase that mediates the ubiquitination of AKT1 and GLUL, thereby playing a role in neuron cells differentiation. Plays a role in the establishment and maintenance of neuronal transmission and plasticity. Regulates Schwann cells differentiation by mediating ubiquitination of GLUL. Promotes neurodegeneration by mediating 'Lys-48'-linked polyubiquitination and subsequent degradation of AKT1 in axons: degradation of AKT1 prevents AKT1-mediated phosphorylation of GSK3B, leading to GSK3B activation and phosphorylation of DPYSL2/CRMP2 followed by destabilization of microtubule assembly in axons (Probable).

    Gene: ZNRF1

    分子量
    24 kDa
    基因ID
    84937
    UniProt
    Q8ND25
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