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- 抗原 See all ZNF598 抗体
- ZNF598 (Zinc Finger Protein 598 (ZNF598))
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抗原表位
- N-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ZNF598 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- ZFP598 Antibody detects endogenous levels of total ZFP598.
- 预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human ZFP598, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product ZNF598 Primary Antibody
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anti-Zinc Finger Protein 598 (ZNF598) (AA 28-126) antibody
ZNF598 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Zinc Finger Protein 598 (ZNF598) (AA 28-126) antibodyZNF598 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 1E2 unconjugated
anti-Zinc Finger Protein 598 (ZNF598) (AA 398-447) antibodyZNF598 适用: 人, 大鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 598 (ZNF598) (AA 578-627) antibodyZNF598 适用: 人, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 598 (ZNF598) (AA 120-420) antibodyZNF598 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 598 (ZNF598) (Middle Region) antibodyZNF598 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 598 (ZNF598) (Middle Region) antibodyZNF598 适用: 人, 小鼠, 大鼠, Cow WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- ZNF598 (Zinc Finger Protein 598 (ZNF598))
- 别名
- ZNF598 (ZNF598 产品)
- 别名
- ZNF598 antibody, BC023040 antibody, Ntrap antibody, Znf598 antibody, Zfp598 antibody, wu:fc88f12 antibody, zinc finger protein 598 antibody, ZNF598 antibody, znf598 antibody, Zfp598 antibody
- 背景
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Description: E3 ubiquitin-protein ligase that plays a key role in the ribosome quality control (RQC), a pathway that takes place when a ribosome has stalled during translation (PubMed:28065601, PubMed:28132843). Required for ribosomes to terminally stall during translation of poly(A) sequences by mediating monoubiquitination of 40S ribosomal protein RPS10/eS10, RPS20/uS10 and RPS3/uS3 (PubMed:28065601, PubMed:28132843). Stalling precludes synthesis of a long poly-lysine tail and initiates the RQC pathway to degrade the potentially detrimental aberrant nascent polypeptide (PubMed:28065601, PubMed:28132843). Also acts as a component of the 4EHP-GYF2 complex, a multiprotein complex that acts as a repressor of translation initiation (PubMed:22751931).
Gene: ZNF598
- 分子量
- 98 kDa
- 基因ID
- 90850
- UniProt
- Q86UK7
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