ZCCHC11 抗体 (Internal Region)
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- 抗原 See all ZCCHC11 抗体
- ZCCHC11 (Zinc Finger, CCHC Domain Containing 11 (ZCCHC11))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ZCCHC11 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- ZCCHC11 Antibody detects endogenous levels of total ZCCHC11.
- 预测反应
- Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human ZCCHC11, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product ZCCHC11 Primary Antibody
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anti-Zinc Finger, CCHC Domain Containing 11 (ZCCHC11) (AA 1-290) antibody
ZCCHC11 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, CCHC Domain Containing 11 (ZCCHC11) (AA 1403-1452) antibodyZCCHC11 适用: 人, 犬, Cow, 豚鼠, Pig, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, CCHC Domain Containing 11 (ZCCHC11) (AA 1-309) antibodyZCCHC11 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Zinc Finger, CCHC Domain Containing 11 (ZCCHC11) (C-Term) antibodyVerified ZCCHC11 适用: 人 ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated
anti-Zinc Finger, CCHC Domain Containing 11 (ZCCHC11) (Internal Region) antibodyVerified ZCCHC11 适用: 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Zinc Finger, CCHC Domain Containing 11 (ZCCHC11) (AA 1568-1600), (C-Term) antibodyZCCHC11 适用: 小鼠 WB 宿主: 兔 Polyclonal RB51164 unconjugated
anti-Zinc Finger, CCHC Domain Containing 11 (ZCCHC11) (AA 1-309) antibodyZCCHC11 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, CCHC Domain Containing 11 (ZCCHC11) (Middle Region) antibodyZCCHC11 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- ZCCHC11 (Zinc Finger, CCHC Domain Containing 11 (ZCCHC11))
- 别名
- ZCCHC11 (ZCCHC11 产品)
- 别名
- PAPD3 antibody, TUT4 antibody, ZCCHC11 antibody, DKFZp459G145 antibody, 6030404K05Rik antibody, 9230115F04Rik antibody, PPAPD3 antibody, mKIAA0191 antibody, wu:fc06h08 antibody, wu:fy37g11 antibody, papd3 antibody, zinc finger CCHC-type containing 11 antibody, zinc finger, CCHC domain containing 11 antibody, zinc finger CCHC domain containing 11 antibody, ZCCHC11 antibody, Zcchc11 antibody, zcchc11 antibody
- 背景
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Description: Uridylyltransferase that mediates the terminal uridylation of mRNAs with short (less than 25 nucleotides) poly(A) tails, hence facilitating global mRNA decay (PubMed:25480299). Involved in microRNA (miRNA)-induced gene silencing through uridylation of deadenylated miRNA targets. Also acts as a suppressor of miRNA biogenesis by mediating the terminal uridylation of some miRNA precursors, including that of let-7 (pre-let-7), miR107, miR-143 and miR-200c. Uridylated miRNAs are not processed by Dicer and undergo degradation. Degradation of pre-let-7 contributes to the maintenance of embryonic stem (ES) cell pluripotency (By similarity). Does not bind RNA directly, but recruited to RNA targets by RNA-binding protein LIN28A. Also catalyzes the 3' uridylation of miR-26A, a miRNA that targets IL6 transcript. This abrogates the silencing of IL6 transcript, hence promoting cytokine expression (By similarity). May also suppress Toll-like receptor-induced NF-kappa-B activation via binding to T2BP. Does not play a role in replication-dependent histone mRNA degradation. Due to functional redundancy between ZCCHC6 and ZCCHC11, the identification of the specific role of each of these proteins is difficult.
Gene: ZCCHC11
- 分子量
- 185 kDa
- 基因ID
- 23318
- UniProt
- Q5TAX3
- 途径
- Stem Cell Maintenance
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