ZBTB17 抗体 (Internal Region)
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- 抗原 See all ZBTB17 抗体
- ZBTB17 (Zinc Finger and BTB Domain Containing 17 (ZBTB17))
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抗原表位
- Internal Region
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ZBTB17 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- ZBTB17 Antibody detects endogenous levels of total ZBTB17.
- 预测反应
- Pig,Bovine,Horse,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human ZBTB17, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product ZBTB17 Primary Antibody
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- 应用备注
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- ZBTB17 (Zinc Finger and BTB Domain Containing 17 (ZBTB17))
- 别名
- ZBTB17 (ZBTB17 产品)
- 别名
- MIZ-1 antibody, ZNF151 antibody, ZNF60 antibody, pHZ-67 antibody, AA589413 antibody, Lp-1 antibody, Miz1 antibody, Zfp100 antibody, mZ13 antibody, Miz-1 antibody, zbtb17 antibody, zinc finger and BTB domain containing 17 antibody, zinc finger and BTB domain containing 17 S homeolog antibody, ZBTB17 antibody, Zbtb17 antibody, zbtb17.S antibody
- 背景
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Description: Transcription factor that can function as an activator or repressor depending on its binding partners, and by targeting negative regulators of cell cycle progression. Plays a critical role in early lymphocyte development, where it is essential to prevent apoptosis in lymphoid precursors, allowing them to survive in response to IL7 and undergo proper lineage commitment. Has been shown to bind to the promoters of adenovirus major late protein and cyclin D1 and activate transcription. Required for early embryonic development during gastrulation. Represses RB1 transcription, this repression can be blocked by interaction with ZBTB49 isoform 3/ZNF509S1 (PubMed:25245946).
Gene: ZBTB17
- 分子量
- 88 kDa
- 基因ID
- 7709
- UniProt
- Q13105
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, ER-Nucleus Signaling
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