YTHDF1 抗体 (N-Term)
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- 抗原 See all YTHDF1 products
- YTHDF1 (YTH Domain Family, Member 1 (YTHDF1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This YTHDF1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- YTHDF1 Antibody detects endogenous levels of total YTHDF1.
- 预测反应
- Pig,Bovine,Horse,Sheep,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human YTHDF1, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
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- 应用备注
- WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- YTHDF1 (YTH Domain Family, Member 1 (YTHDF1))
- 别名
- YTHDF1 (YTHDF1 产品)
- 别名
- fb49c02 antibody, zgc:55657 antibody, wu:fb49c02 antibody, wu:fi19h06 antibody, wu:fj87f09 antibody, wu:fp06c11 antibody, MGC75606 antibody, MGC68505 antibody, 2210410K23Rik antibody, 8030473O16 antibody, C20orf21 antibody, YTH N(6)-methyladenosine RNA binding protein 1 antibody, YTH N(6)-methyladenosine RNA binding protein 1 L homeolog antibody, YTH N6-methyladenosine RNA binding protein 1 antibody, YTH domain family 1 antibody, ythdf1 antibody, ythdf1.L antibody, YTHDF1 antibody, Ythdf1 antibody
- 背景
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Description: Specifically recognizes and binds N6-methyladenosine (m6A)-containing mRNAs, and promotes mRNA translation efficiency (PubMed:24284625, PubMed:26046440, PubMed:26318451). M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability (PubMed:24284625). Acts as a regulator of mRNA translation efficiency: promotes ribosome loading to m6A-containing mRNAs and interacts with translation initiation factors eIF3 (EIF3A or EIF3B) to facilitate translation initiation (PubMed:26046440).
Gene: YTHDF1
- 分子量
- 61kDa
- 基因ID
- 54915
- UniProt
- Q9BYJ9
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