XPO4 抗体 (N-Term)
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- 抗原 See all XPO4 抗体
- XPO4 (Exportin 4 (XPO4))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This XPO4 antibody is un-conjugated
- 应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- 特异性
- XPO4 Antibody detects endogenous levels of total XPO4.
- 预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human XPO4, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
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- 应用备注
- WB 1:1000-3000, IHC 1:200, IF/ICC 1:200-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- XPO4 (Exportin 4 (XPO4))
- 别名
- XPO4 (XPO4 产品)
- 别名
- XPO4 antibody, MGC157258 antibody, DDBDRAFT_0215248 antibody, DDBDRAFT_0237580 antibody, DDB_0215248 antibody, DDB_0237580 antibody, exp4 antibody, B430309A01Rik antibody, mKIAA1721 antibody, fc26b07 antibody, wu:fc26b07 antibody, wu:fi43b10 antibody, zgc:55678 antibody, exportin 4 antibody, exportin 4 L homeolog antibody, XPO4 antibody, xpo4 antibody, Xpo4 antibody, xpo4.L antibody
- 背景
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Description: Mediates the nuclear export of proteins (cargos) with broad substrate specificity. In the nucleus binds cooperatively to its cargo and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor. XPO4 then return to the nuclear compartment and mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.
Gene: XPO4
- 分子量
- 127 kDa
- 基因ID
- 64328
- UniProt
- Q9C0E2
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