Lysine (K)-Specific Methyltransferase 2B (KMT2B) (C-Term) 抗体
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- 抗原 See all Lysine (K)-Specific Methyltransferase 2B (KMT2B) 抗体
- Lysine (K)-Specific Methyltransferase 2B (KMT2B)
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抗原表位
- C-Term
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- 非结合性
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应用范围
- ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- WBP7 Antibody detects endogenous levels of total WBP7.
- 预测反应
- Bovine,Horse,Sheep,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human WBP7, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product KMT2B Primary Antibody
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- 应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- Lysine (K)-Specific Methyltransferase 2B (KMT2B)
- 别名
- KMT2B (KMT2B 产品)
- 别名
- HRX2 antibody, MLL1B antibody, MLL2 antibody, MLL4 antibody, TRX2 antibody, WBP7 antibody, lysine methyltransferase 2B antibody, KMT2B antibody
- 背景
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Description: Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in beta-globin locus transcription regulation by being recruited by NFE2. Plays an important role in controlling bulk H3K4me during oocyte growth and preimplantation development. Required during the transcriptionally active period of oocyte growth for the establishment and/or maintenance of bulk H3K4 trimethylation (H3K4me3), global transcriptional silencing that preceeds resumption of meiosis, oocyte survival and normal zygotic genome activation.
Gene: KMT2B
- 分子量
- 294kDa
- 基因ID
- 9757
- UniProt
- Q9UMN6
- 途径
- Warburg Effect
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