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- 抗原 See all MAVS 抗体
- MAVS (Mitochondrial Antiviral Signaling Protein (MAVS))
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抗原表位
- C-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MAVS antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- VISA Antibody detects endogenous levels of total VISA.
- 预测反应
- Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human VISA, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product MAVS Primary Antibody
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anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 1-65) antibody
MAVS 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 34-96) antibodyMAVS 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 1-540) antibodyMAVS 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 160-450) antibodyMAVS 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal Adri-1 unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (N-Term) antibodyMAVS 适用: 人, 小鼠, Cow WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 160-450) antibodyMAVS 适用: 人 WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 470-519) antibodyMAVS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 146-195) antibodyMAVS 适用: 人, 小鼠, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 1-30), (N-Term) antibodyMAVS 适用: 小鼠 WB 宿主: 兔 Polyclonal RB42373 unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 1-30) antibodyMAVS 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- MAVS (Mitochondrial Antiviral Signaling Protein (MAVS))
- 别名
- MAVS (MAVS 产品)
- 别名
- CARDIF antibody, IPS-1 antibody, IPS1 antibody, VISA antibody, D430028G21Rik antibody, Visa antibody, cardif antibody, wu:fj20d04 antibody, zgc:158392 antibody, mitochondrial antiviral signaling protein antibody, MAVS antibody, Mavs antibody, mavs antibody
- 背景
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Description: Required for innate immune defense against viruses. Acts downstream of DHX33, DDX58/RIG-I and IFIH1/MDA5, which detect intracellular dsRNA produced during viral replication, to coordinate pathways leading to the activation of NF-kappa-B, IRF3 and IRF7, and to the subsequent induction of antiviral cytokines such as IFN-beta and RANTES (CCL5). Peroxisomal and mitochondrial MAVS act sequentially to create an antiviral cellular state. Upon viral infection, peroxisomal MAVS induces the rapid interferon-independent expression of defense factors that provide short-term protection, whereas mitochondrial MAVS activates an interferon-dependent signaling pathway with delayed kinetics, which amplifies and stabilizes the antiviral response. May activate the same pathways following detection of extracellular dsRNA by TLR3. May protect cells from apoptosis.
Gene: MAVS
- 分子量
- 70-75 kDa
- 基因ID
- 57506
- UniProt
- Q7Z434
- 途径
- Activation of Innate immune Response, Inositol Metabolic Process, Hepatitis C
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