USP9X 抗体 (N-Term)
-
- 抗原 See all USP9X 抗体
- USP9X (Ubiquitin Specific Peptidase 9, X-Linked (USP9X))
-
抗原表位
- N-Term
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This USP9X antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 特异性
- USP9X Antibody detects endogenous levels of total USP9X.
- 预测反应
- Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human USP9X, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product USP9X Primary Antibody
-
-
- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
-
- 抗原
- USP9X (Ubiquitin Specific Peptidase 9, X-Linked (USP9X))
- 别名
- USP9X (USP9X 产品)
- 别名
- DFFRX antibody, FAF antibody, FAM antibody, RGD1560056 antibody, faf antibody, fam antibody, dffrx antibody, 5730589N07Rik antibody, AA407302 antibody, AA407699 antibody, AL022658 antibody, AL022749 antibody, Dffrx antibody, FAF-X antibody, Fafl antibody, ubiquitin specific peptidase 9, X-linked antibody, ubiquitin specific peptidase 9, X chromosome antibody, USP9X antibody, Usp9x antibody, usp9x antibody
- 背景
-
Description: Deubiquitinase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Specifically hydrolyzes 'Lys-48'-, 'Lys-29'- and 'Lys-33'-linked polyubiquitins chains. Essential component of TGF-beta/BMP signaling cascade. Specifically deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Deubiquitinates alkylation repair enzyme ALKBH3. OTUD4 recruits USP7 and USP9X to stabilize ALKBH3, thereby promoting the repair of alkylated DNA lesions (PubMed:25944111). Regulates chromosome alignment and segregation in mitosis by regulating the localization of BIRC5/survivin to mitotic centromeres. Involved in axonal growth and neuronal cell migration (PubMed:16322459, PubMed:18254724, PubMed:19135894, PubMed:24607389).
Gene: USP9X
- 分子量
- 260-290 kDa
- 基因ID
- 8239
- UniProt
- Q93008
-