USP33 抗体 (Internal Region)
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- 抗原 See all USP33 抗体
- USP33 (Ubiquitin Specific Peptidase 33 (USP33))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This USP33 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Western Blotting (WB)
- 特异性
- USP33 Antibody detects endogenous levels of total USP33.
- 预测反应
- Bovine,Horse,Sheep,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human USP33, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product USP33 Primary Antibody
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anti-Ubiquitin Specific Peptidase 33 (USP33) (AA 327-426) antibody
USP33 适用: 人 ELISA, WB, IF, IHC (p), IP 宿主: 小鼠 Monoclonal 5B5 unconjugated
anti-Ubiquitin Specific Peptidase 33 (USP33) antibodyUSP33 适用: 人, 小鼠, 大鼠 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 33 (USP33) (AA 290-400) antibodyUSP33 适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 33 (USP33) (AA 251-550), (C-Term) antibodyUSP33 适用: 人 ELISA, IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 33 (USP33) (AA 1-911) antibodyUSP33 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 33 (USP33) (Internal Region) antibodyUSP33 适用: 人, Cow, 犬, 兔, 马, Bat IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 33 (USP33) (AA 327-427) antibodyUSP33 适用: 人 ELISA, IHC, WB, IF, IHC (p), IP 宿主: 小鼠 Monoclonal 5B5 unconjugated
anti-Ubiquitin Specific Peptidase 33 (USP33) (AA 799-829) antibodyUSP33 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- USP33 (Ubiquitin Specific Peptidase 33 (USP33))
- 别名
- USP33 (USP33 产品)
- 别名
- USP33 antibody, VDU1 antibody, 9830169D19Rik antibody, AA409780 antibody, Vdu1 antibody, zgc:77308 antibody, ubiquitin specific peptidase 33 antibody, universal stress protein UspA antibody, Usp33 antibody, USP33 antibody, RR_RS17870 antibody, usp33 antibody
- 背景
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Description: Deubiquitinating enzyme involved in various processes such as centrosome duplication, cellular migration and beta-2 adrenergic receptor/ADRB2 recycling. Involved in regulation of centrosome duplication by mediating deubiquitination of CCP110 in S and G2/M phase, leading to stabilize CCP110 during the period which centrioles duplicate and elongate. Involved in cell migration via its interaction with intracellular domain of ROBO1, leading to regulate the Slit signaling. Plays a role in commissural axon guidance cross the ventral midline of the neural tube in a Slit-dependent manner, possibly by mediating the deubiquitination of ROBO1. Acts as a regulator of G-protein coupled receptor (GPCR) signaling by mediating the deubiquitination of beta-arrestins (ARRB1 and ARRB2) and beta-2 adrenergic receptor (ADRB2). Plays a central role in ADRB2 recycling and resensitization after prolonged agonist stimulation by constitutively binding ADRB2, mediating deubiquitination of ADRB2 and inhibiting lysosomal trafficking of ADRB2. Upon dissociation, it is probably transferred to the translocated beta-arrestins, leading to beta-arrestins deubiquitination and disengagement from ADRB2. This suggests the existence of a dynamic exchange between the ADRB2 and beta-arrestins. Deubiquitinates DIO2, thereby regulating thyroid hormone regulation. Mediates deubiquitination of both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Gene: USP33
- 分子量
- 103 kDa,107 kDa
- 基因ID
- 23032
- UniProt
- Q8TEY7
- 途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
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