USP16 抗体 (N-Term)
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- 抗原 See all USP16 抗体
- USP16 (Ubiquitin Specific Peptidase 16 (USP16))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This USP16 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- USP16 Antibody detects endogenous levels of total USP16.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human USP16, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
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- 应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- USP16 (Ubiquitin Specific Peptidase 16 (USP16))
- 别名
- USP16 (USP16 产品)
- 别名
- ubp-m antibody, USP16 antibody, UBP-M antibody, 1200004E02Rik antibody, 2810483I07Rik antibody, 6330514E22Rik antibody, UBPM antibody, si:ch211-238e22.5 antibody, si:dkey-121n8.2 antibody, wu:fc76b02 antibody, wu:fc76b08 antibody, universal stress protein antibody, ubiquitin specific peptidase 16 antibody, ubiquitin specific peptidase 16 L homeolog antibody, usp16 antibody, USP16 antibody, Usp16 antibody, usp16.L antibody
- 背景
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Description: Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. In resting B- and T-lymphocytes, phosphorylation by AURKB leads to enhance its activity, thereby maintaining transcription in resting lymphocytes. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B.
Gene: USP16
- 分子量
- 94 kDa
- 基因ID
- 10600
- UniProt
- Q9Y5T5
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