Urm1 抗体 (Internal Region)
-
- 抗原 See all Urm1 抗体
- Urm1 (Ubiquitin Related Modifier 1 (Urm1))
-
抗原表位
- Internal Region
-
适用
- 人, 大鼠, 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This Urm1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- URM1 Antibody detects endogenous levels of total URM1.
- 预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human URM1, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product Urm1 Primary Antibody
-
-
- 应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
-
- 抗原
- Urm1 (Ubiquitin Related Modifier 1 (Urm1))
- 别名
- URM1 (Urm1 产品)
- 别名
- RGD1306599 antibody, C9orf74 antibody, 2900073H19Rik antibody, ubiquitin related modifier 1 antibody, ubiquitin related modifier antibody, ubiquitin-related modifier antibody, Ubiquitin-related modifier 1 homolog antibody, Urm1 antibody, LOC733109 antibody, URM1 antibody
- 背景
-
Description: Acts as a sulfur carrier required for 2-thiolation of mcm5S2U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm5S2U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as MOCS3, ATPBD3, CTU2, USP15 and CAS. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
Gene: URM1
- 分子量
- 11 kDa
- 基因ID
- 81605
- UniProt
- Q9BTM9
-