UFD1L 抗体 (Internal Region)
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- 抗原 See all UFD1L 抗体
- UFD1L (Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This UFD1L antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- UFD1L Antibody detects endogenous levels of total UFD1L.
- 预测反应
- Pig,Horse,Rabbit,Dog,Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human UFD1L, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product UFD1L Primary Antibody
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anti-Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L) (full length) antibody
UFD1L 适用: 人, 小鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L) (AA 208-307) antibodyUFD1L 适用: 人 IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 4F11A4 unconjugated
anti-Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L) (AA 208-307) antibodyUFD1L 适用: 人 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 2A6F3 unconjugated
anti-Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L) (AA 1-307) antibodyUFD1L 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L) (AA 1-307) antibodyUFD1L 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L) antibodyUFD1L 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L) (AA 161-210) antibodyUFD1L 适用: 人, 大鼠, 犬, 豚鼠, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L) antibodyUFD1L 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- UFD1L (Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))
- 别名
- UFD1 (UFD1L 产品)
- 别名
- UFD1 antibody, Ufd1 antibody, ufd1 antibody, wu:fc55f04 antibody, zgc:92341 antibody, Ufd1l antibody, ubiquitin recognition factor in ER associated degradation 1 antibody, ubiquitin recognition factor in ER-associated degradation 1 antibody, ubiquitin fusion degradation 1 like (yeast) antibody, ubiquitin recognition factor in ER associated degradation 1 S homeolog antibody, ubiquitin fusion degradation protein 1 homolog antibody, Ubiquitin Fusion Degradation (yeast UFD homolog) antibody, UFD1 antibody, Ufd1 antibody, UFD1L antibody, ufd1.S antibody, ufd1l antibody, ufd1 antibody, EHI_125920 antibody, LOC100166745 antibody, LOC100635687 antibody, LOC100648660 antibody, ufd-1 antibody
- 背景
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Description: Essential component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. The ternary complex containing UFD1, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. It may be involved in the development of some ectoderm-derived structures (By similarity). Acts as a negative regulator of type I interferon production via the complex formed with VCP and NPLOC4, which binds to DDX58/RIG-I and recruits RNF125 to promote ubiquitination and degradation of DDX58/RIG-I (PubMed:26471729).
Gene: UFD1
- 分子量
- 35 kDa
- 基因ID
- 7353
- UniProt
- Q92890
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