UCP1 抗体 (Internal Region)
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- 抗原 See all UCP1 抗体
- UCP1 (Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This UCP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- 特异性
- UCP1 Antibody detects endogenous levels of total UCP1.
- 预测反应
- Bovine,Horse,Sheep,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human UCP1, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product UCP1 Primary Antibody
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- 应用备注
- WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- UCP1 (Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1))
- 别名
- UCP1 (UCP1 产品)
- 别名
- ARABIDOPSIS THALIANA PLANT UNCOUPLING MITOCHONDRIAL PROTEIN 1 antibody, ARABIDOPSIS THALIANA UNCOUPLING PROTEIN 1 antibody, ATPUMP1 antibody, ATUCP1 antibody, UCP antibody, UCP1 antibody, UNCOUPLING PROTEIN 1 antibody, plant uncoupling mitochondrial protein 1 antibody, ucp antibody, slc25a7 antibody, SLC25A7 antibody, AI385626 antibody, Slc25a7 antibody, Ucp antibody, Ucpa antibody, Uncp antibody, plant uncoupling mitochondrial protein 1 antibody, uncoupling protein 1 antibody, uncoupling protein 1 L homeolog antibody, uncoupling protein 1 (mitochondrial, proton carrier) antibody, PUMP1 antibody, UCP1 antibody, ucp1.L antibody, ucp1 antibody, Ucp1 antibody
- 背景
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Description: Mitochondrial protein responsible for thermogenic respiration, a specialized capacity of brown adipose tissue and beige fat that participates to non-shivering adaptive thermogenesis to temperature and diet variations and more generally to the regulation of energy balance (By similarity). Functions as a long-chain fatty acid/LCFA and proton symporter, simultaneously transporting one LCFA and one proton through the inner mitochondrial membrane (PubMed:24196960). However, LCFAs remaining associated with the transporter via their hydrophobic tails, it results in an apparent transport of protons activated by LCFAs. Thereby, dissipates the mitochondrial proton gradient and converts the energy of substrate oxydation into heat instead of ATP. Regulates the production of reactive oxygen species/ROS by mitochondria (By similarity).
Gene: UCP1
- 分子量
- 34 kDa
- 基因ID
- 7350
- UniProt
- P25874
- 途径
- Proton Transport, Brown Fat Cell Differentiation
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