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TUT1 抗体 (N-Term)

TUT1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6265809
发货至: 中国
  • 抗原 See all TUT1 抗体
    TUT1 (Terminal Uridylyl Transferase 1, U6 SnRNA-Specific (TUT1))
    抗原表位
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 15
    • 10
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 15
    克隆类型
    • 15
    多克隆
    标记
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TUT1 antibody is un-conjugated
    应用范围
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    特异性
    TUTase Antibody detects endogenous levels of total TUTase.
    预测反应
    Bovine,Horse,Rabbit,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human TUTase, corresponding to a region within N-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product TUT1 Primary Antibody
  • 应用备注
    WB 1:1000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    TUT1 (Terminal Uridylyl Transferase 1, U6 SnRNA-Specific (TUT1))
    别名
    TUT1 (TUT1 产品)
    别名
    PAPD2 antibody, RBM21 antibody, STARPAP antibody, TUTase antibody, 2700038E08Rik antibody, Rbm21 antibody, zgc:112254 antibody, terminal uridylyl transferase 1, U6 snRNA-specific antibody, TUT1 antibody, Tut1 antibody, tut1 antibody
    背景

    Description: Poly(A) polymerase that creates the 3'-poly(A) tail of specific pre-mRNAs. Localizes to nuclear speckles together with PIP5K1A and mediates polyadenylation of a select set of mRNAs, such as HMOX1. In addition to polyadenylation, it is also required for the 3'-end cleavage of pre-mRNAs: binds to the 3'UTR of targeted pre-mRNAs and promotes the recruitment and assembly of the CPSF complex on the 3'UTR of pre-mRNAs. In addition to adenylyltransferase activity, also has uridylyltransferase activity. However, the ATP ratio is higher than UTP in cells, suggesting that it functions primarily as a poly(A) polymerase. Acts as a specific terminal uridylyltransferase for U6 snRNA in vitro: responsible for a controlled elongation reaction that results in the restoration of the four 3'-terminal UMP-residues found in newly transcribed U6 snRNA. Not involved in replication-dependent histone mRNA degradation.

    Gene: TUT1

    分子量
    95kDa
    基因ID
    64852
    UniProt
    Q9H6E5
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