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TSG101 抗体

TSG101 适用: 人, 猴 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6265767
发货至: 中国
  • 抗原 See all TSG101 抗体
    TSG101 (Tumor Susceptibility Gene 101 (TSG101))
    适用
    • 70
    • 41
    • 30
    • 11
    • 9
    • 8
    • 8
    • 8
    • 6
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    • 4
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    人, 猴
    宿主
    • 61
    • 12
    克隆类型
    • 53
    • 20
    多克隆
    标记
    • 48
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
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    This TSG101 antibody is un-conjugated
    应用范围
    • 58
    • 29
    • 25
    • 13
    • 11
    • 11
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    TSG101 Antibody detects endogenous levels of total TSG101
    交叉反应
    人, 猴
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human TSG101
    亚型
    IgG
    Top Product
    Discover our top product TSG101 Primary Antibody
  • 应用备注
    WB 1:1000-3000, IF/ICC 1:100-1:500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C.Stable for 12 months from date of receipt
    有效期
    12 months
  • 抗原
    TSG101 (Tumor Susceptibility Gene 101 (TSG101))
    别名
    TSG101 (TSG101 产品)
    背景

    Description: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis, the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses. Required for the exosomal release of SDCBP, CD63 and syndecan (PubMed:22660413). It may also play a role in the extracellular release of microvesicles that differ from the exosomes (PubMed:22315426).

    Gene: TSG101

    分子量
    45 kDa
    基因ID
    7251
    UniProt
    Q99816
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