TRIP13 抗体 (C-Term)
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- 抗原 See all TRIP13 抗体
- TRIP13 (Thyroid Hormone Receptor Interactor 13 (TRIP13))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TRIP13 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
- 特异性
- TRIP13 Antibody detects endogenous levels of total TRIP13.
- 预测反应
- Pig,Bovine,Horse,Sheep,Dog,Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human TRIP13, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product TRIP13 Primary Antibody
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- 应用备注
- WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- TRIP13 (Thyroid Hormone Receptor Interactor 13 (TRIP13))
- 别名
- TRIP13 (TRIP13 产品)
- 别名
- im:6901078 antibody, zgc:65952 antibody, 16e1bp antibody, pch2 antibody, trip-13 antibody, TRIP13 antibody, 16E1BP antibody, PCH2 antibody, TRIP-13 antibody, 2410002G23Rik antibody, D13Ertd328e antibody, thyroid hormone receptor interactor 13 antibody, pachytene checkpoint protein 2 homolog antibody, pachytene checkpoint protein 2 homolog pseudogene antibody, thyroid hormone receptor interactor 13 L homeolog antibody, trip13 antibody, TRIP13 antibody, LOC742208 antibody, CMU_027690 antibody, MCYG_05496 antibody, LOC100348391 antibody, trip13.L antibody, Trip13 antibody
- 背景
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Description: Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for sex body formation. Promotes early steps of the DNA double-strand breaks (DSBs) repair process upstream of the assembly of RAD51 complexes. Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes (By similarity). Plays a role in mitotic spindle assembly checkpoint (SAC) activation (PubMed:28553959).
Gene: TRIP13
- 分子量
- 48kDa
- 基因ID
- 9319
- UniProt
- Q15645
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