TRIP10 抗体 (Internal Region)
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- 抗原 See all TRIP10 抗体
- TRIP10 (Thyroid Hormone Receptor Interactor 10 (TRIP10))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TRIP10 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- TRIP10 Antibody detects endogenous levels of total TRIP10.
- 预测反应
- Pig,Bovine,Horse,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human TRIP10, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product TRIP10 Primary Antibody
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- 应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- TRIP10 (Thyroid Hormone Receptor Interactor 10 (TRIP10))
- 别名
- TRIP10 (TRIP10 产品)
- 别名
- CIP4 antibody, HSTP antibody, STOT antibody, STP antibody, AI646975 antibody, Cip4 antibody, trip10 antibody, thyroid hormone receptor interactor 10 antibody, thyroid hormone receptor interactor 10a antibody, TRIP10 antibody, Trip10 antibody, trip10a antibody
- 背景
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Description: Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling (By similarity). Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.
Gene: TRIP10
- 分子量
- 68 kDa
- 基因ID
- 9322
- UniProt
- Q15642
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