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TRIM14 抗体 (C-Term)

TRIM14 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6265727
发货至: 中国
  • 抗原 See all TRIM14 抗体
    TRIM14 (Tripartite Motif Containing 14 (TRIM14))
    抗原表位
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 18
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 17
    • 1
    克隆类型
    • 18
    多克隆
    标记
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TRIM14 antibody is un-conjugated
    应用范围
    • 11
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    TRIM14 Antibody detects endogenous levels of total TRIM14.
    预测反应
    Pig,Bovine,Rabbit
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human TRIM14, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product TRIM14 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    TRIM14 (Tripartite Motif Containing 14 (TRIM14))
    别名
    TRIM14 (TRIM14 产品)
    别名
    TRIM14 antibody, 5830400N10Rik antibody, pub antibody, tripartite motif containing 14 antibody, tripartite motif-containing 14 antibody, TRIM14 antibody, Trim14 antibody
    背景

    Description: Plays a role in the innate immune defense against viruses. Facilitates the type I IFN response by interacting with MAVS at the outer mitochondria membrane and thereby recruiting NF-kappa-B essential modulator IKBKG/NEMO to the MAVS signalosome, leading to the activation of both the IFN regulatory factor 3/IRF3 and NF-kappa-B pathways (PubMed:24379373). Positively regulates the CGAS-induced type I interferon signaling pathway by stabilizing CGAS and inhibiting its autophagic degradation (PubMed:27666593).

    Gene: TRIM14

    分子量
    50 kDa
    基因ID
    9830
    UniProt
    Q14142
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