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TRIB3 抗体 (N-Term)

TRIB3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6265726
发货至: 中国
  • 抗原 See all TRIB3 抗体
    TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))
    抗原表位
    • 16
    • 12
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    • 8
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    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
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    N-Term
    适用
    • 68
    • 27
    • 22
    • 3
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    • 2
    • 2
    • 2
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    宿主
    • 75
    • 5
    克隆类型
    • 77
    • 3
    多克隆
    标记
    • 35
    • 7
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    • 6
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    • 4
    • 1
    • 1
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    This TRIB3 antibody is un-conjugated
    应用范围
    • 52
    • 40
    • 14
    • 13
    • 13
    • 12
    • 11
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    特异性
    TRIB3 Antibody detects endogenous levels of total TRIB3.
    预测反应
    Pig,Bovine,Sheep
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human TRIB3, corresponding to a region within N-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product TRIB3 Primary Antibody
  • 应用备注
    WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))
    别名
    TRIB3 (TRIB3 产品)
    别名
    zgc:76966 antibody, TRIB3 antibody, C20orf97 antibody, NIPK antibody, SINK antibody, SKIP3 antibody, TRB3 antibody, Ifld2 antibody, Nipk antibody, TRB-3 antibody, Trb3 antibody, tribbles pseudokinase 3 antibody, trib3 antibody, TRIB3 antibody, Trib3 antibody
    背景

    Description: Disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. May bind directly to and mask the 'Thr-308' phosphorylation site in AKT1. Binds to ATF4 and inhibits its transcriptional activation activity. Interacts with the NF-kappa-B transactivator p65 RELA and inhibits its phosphorylation and thus its transcriptional activation activity. Interacts with MAPK kinases and regulates activation of MAP kinases. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells. Does not display kinase activity. Inhibits the transcriptional activity of DDIT3/CHOP and is involved in DDIT3/CHOP-dependent cell death during ER stress. Can inhibit APOBEC3A editing of nuclear DNA.

    Gene: TRIB3

    分子量
    40 kDa
    基因ID
    57761
    UniProt
    Q96RU7
    途径
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
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