TRF1 抗体 (Internal Region)
-
- 抗原 See all TRF1 (TERF1) 抗体
- TRF1 (TERF1) (Telomeric Repeat Binding Factor (NIMA-Interacting) 1 (TERF1))
-
抗原表位
- Internal Region
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This TRF1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- TRF1 Antibody detects endogenous levels of total TRF1.
- 预测反应
- Horse,Sheep
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human TRF1, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product TERF1 Primary Antibody
-
-
- 应用备注
- WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
-
- 抗原
- TRF1 (TERF1) (Telomeric Repeat Binding Factor (NIMA-Interacting) 1 (TERF1))
- 别名
- TERF1 (TERF1 产品)
- 别名
- PIN2 antibody, TRBF1 antibody, TRF antibody, TRF1 antibody, hTRF1-AS antibody, t-TRF1 antibody, wu:fb74c04 antibody, TERF1 antibody, DKFZp459A0713 antibody, Pin2 antibody, Trbf1 antibody, Trf1 antibody, terf1 antibody, trf1 antibody, telomeric repeat binding factor 1 antibody, telomeric repeat binding factor (NIMA-interacting) 1 antibody, telomeric repeat binding factor (NIMA-interacting) 1 L homeolog antibody, TERF1 antibody, Terf1 antibody, terf1 antibody, Trf1 antibody, terf1.L antibody
- 背景
-
Description: Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and negatively regulates telomere length. Involved in the regulation of the mitotic spindle. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded 5'-TTAGGG-3' repeats added by telomerase and protects chromosome ends, without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways.
Gene: TERF1
- 分子量
- 50kDa
- 基因ID
- 7013
- UniProt
- P54274
- 途径
- Cell Division Cycle, Telomere Maintenance, Hormone Transport, Chromatin Binding, Regulation of Cell Size, Positive Regulation of Endopeptidase Activity
-