TARBP2 抗体 (Internal Region)
-
- 抗原 See all TARBP2 抗体
- TARBP2 (TAR (HIV-1) RNA Binding Protein 2 (TARBP2))
-
抗原表位
- Internal Region
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This TARBP2 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- TRBP Antibody detects endogenous levels of total TRBP.
- 预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human TRBP, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product TARBP2 Primary Antibody
-
-
- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
-
- 抗原
- TARBP2 (TAR (HIV-1) RNA Binding Protein 2 (TARBP2))
- 别名
- TARBP2 (TARBP2 产品)
- 别名
- trbp antibody, trbp1 antibody, trbp2 antibody, MGC97783 antibody, TARBP2 antibody, LOQS antibody, TRBP antibody, TRBP1 antibody, TRBP2 antibody, fj51e12 antibody, wu:fj51e12 antibody, zgc:63778 antibody, Prbp antibody, TAR (HIV-1) RNA binding protein 2 antibody, TARBP2, RISC loading complex RNA binding subunit antibody, TAR (HIV-1) RNA binding protein 2 L homeolog antibody, TAR (HIV) RNA binding protein 2 antibody, tarbp2 antibody, TARBP2 antibody, tarbp2.L antibody, Tarbp2 antibody
- 背景
-
Description: Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1. Binds to the HIV-1 TAR RNA which is located in the long terminal repeat (LTR) of HIV-1, and stimulates translation of TAR-containing RNAs. This is achieved in part at least by binding to and inhibiting EIF2AK2/PKR, thereby reducing phosphorylation and inhibition of EIF2S1/eIF-2-alpha. May also promote translation of TAR-containing RNAs independently of EIF2AK2/PKR.
Gene: TARBP2
- 分子量
- 43-46 kDa
- 基因ID
- 6895
- UniProt
- Q15633
- 途径
- Regulatory RNA Pathways, Ribonucleoprotein Complex Subunit Organization
-