TRADD 抗体
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- 抗原 See all TRADD 抗体
- TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))
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适用
- 人, 小鼠, 猴
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TRADD antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- TRADD antibody detects endogenous levels of total TRADD
- 交叉反应
- 人, 猴, 小鼠
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human TRADD
- 亚型
- IgG
- Top Product
- Discover our top product TRADD Primary Antibody
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- 应用备注
- WB: 1:500~1:3000 IHC: 1:50~1:200, IF/ICC 1:100-1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
- 有效期
- 12 months
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- 抗原
- TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))
- 别名
- TRADD (TRADD 产品)
- 别名
- TRADD antibody, Hs.89862 antibody, 9130005N23Rik antibody, AA930854 antibody, wu:fc59e02 antibody, zgc:103556 antibody, tradd antibody, TNFRSF1A associated via death domain antibody, conjugal transfer protein D antibody, TNFRSF1A-associated via death domain antibody, TNFRSF1A-associated via death domain L homeolog antibody, tnfrsf1a-associated via death domain antibody, TRADD antibody, traDd antibody, Tradd antibody, tradd.L antibody, tradd antibody
- 背景
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Description: The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A (By similarity). Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.
Gene: TRADD
- 分子量
- 34kDa
- 基因ID
- 8717
- UniProt
- Q15628
- 途径
- NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Hepatitis C
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