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TPMT 抗体 (N-Term)

TPMT 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6265692
发货至: 中国
  • 抗原 See all TPMT 抗体
    TPMT (Thiopurine S-Methyltransferase (TPMT))
    抗原表位
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 41
    • 11
    • 10
    • 2
    • 2
    人, 小鼠, 大鼠
    宿主
    • 32
    • 9
    克隆类型
    • 30
    • 11
    多克隆
    标记
    • 24
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TPMT antibody is un-conjugated
    应用范围
    • 29
    • 18
    • 15
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    特异性
    TPMT Antibody detects endogenous levels of total TPMT.
    预测反应
    Bovine,Horse,Rabbit
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human TPMT, corresponding to a region within N-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product TPMT Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    TPMT (Thiopurine S-Methyltransferase (TPMT))
    别名
    TPMT (TPMT 产品)
    背景

    Description: Catalyzes the S-methylation of thiopurine drugs such as 6-mercaptopurine (also called mercaptopurine, 6-MP or its brand name Purinethol) and 6-thioguanine (also called tioguanine or 6-TG) using S-adenosyl-L-methionine as the methyl donor (PubMed:657528, PubMed:18484748). TPMT activity modulates the cytotoxic effects of thiopurine prodrugs. A natural substrate for this enzyme has yet to be identified.

    Gene: TPMT

    分子量
    28kDa
    基因ID
    7172
    UniProt
    P51580
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