电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

TOPBP1 抗体 (Internal Region)

TOPBP1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6265675
发货至: 中国
  • 抗原 See all TOPBP1 抗体
    TOPBP1 (Topoisomerase (DNA) II Binding Protein 1 (TOPBP1))
    抗原表位
    • 14
    • 12
    • 7
    • 6
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 50
    • 13
    • 9
    人, 小鼠
    宿主
    • 47
    • 3
    • 2
    克隆类型
    • 50
    • 2
    多克隆
    标记
    • 25
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TOPBP1 antibody is un-conjugated
    应用范围
    • 27
    • 27
    • 15
    • 9
    • 4
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    特异性
    TOPBP1 Antibody detects endogenous levels of total TOPBP1.
    预测反应
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human TOPBP1, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product TOPBP1 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    TOPBP1 (Topoisomerase (DNA) II Binding Protein 1 (TOPBP1))
    别名
    TOPBP1 (TOPBP1 产品)
    别名
    RGD1562949 antibody, TOPBP1 antibody, cut5 antibody, F2P24.3 antibody, F2P24_3 antibody, meiosis defective 1 antibody, TOP2BP1 antibody, 1110031N14Rik antibody, 2810429C13Rik antibody, AI256758 antibody, D430026L04Rik antibody, mKIAA0259 antibody, TopBP1-A antibody, TopBP1-B antibody, Xmus101 antibody, XtopBP antibody, mus101 antibody, top2bp1 antibody, DNA topoisomerase II binding protein 1 antibody, topoisomerase (DNA) II binding protein 1 antibody, dna topoisomerase ii binding protein 1 (IC) antibody, transcription coactivator antibody, DNA topoisomerase II binding protein 1 L homeolog antibody, Topbp1 antibody, topbp1 antibody, TOPBP1 antibody, MEI1 antibody, topbp1.L antibody
    背景

    Description: Required for DNA replication. Plays a role in the rescue of stalled replication forks and checkpoint control. Binds double-stranded DNA breaks and nicks as well as single-stranded DNA. Recruits the SWI/SNF chromatin remodeling complex to E2F1-responsive promoters. Down-regulates E2F1 activity and inhibits E2F1-dependent apoptosis during G1/S transition and after DNA damage. Induces a large increase in the kinase activity of ATR (PubMed:16530042).

    Gene: TOPBP1

    分子量
    173kDa
    基因ID
    11073
    UniProt
    Q92547
    途径
    Chromatin Binding
You are here:
客服