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PAR1 抗体 (N-Term)

F2R 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6265563
发货至: 中国
  • 抗原 See all PAR1 (F2R) 抗体
    PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))
    抗原表位
    • 16
    • 15
    • 8
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    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    N-Term
    适用
    • 75
    • 24
    • 22
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 大鼠, 小鼠
    宿主
    • 68
    • 7
    • 2
    克隆类型
    • 71
    • 6
    多克隆
    标记
    • 40
    • 7
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
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    • 1
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    • 1
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    • 1
    • 1
    • 1
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    This PAR1 antibody is un-conjugated
    应用范围
    • 59
    • 34
    • 13
    • 13
    • 10
    • 8
    • 8
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
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    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    特异性
    Thrombin Receptor Antibody detects endogenous levels of total Thrombin Receptor.
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human Thrombin Receptor, corresponding to a region within N-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product F2R Primary Antibody
  • 应用备注
    WB: 1:500-1:3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • Zhao, Zheng, Liu, Luo, Wu, Liu, Zou: "Inhibiting trophoblast PAR-1 overexpression suppresses sFlt-1-induced anti-angiogenesis and abnormal vascular remodeling: a possible therapeutic approach for preeclampsia." in: Molecular human reproduction, Vol. 24, Issue 3, pp. 158-169, (2018) (PubMed).

    Zhong, Chen, Zhang, Xiao, Qin, Gu, Sun, Liu, Jing, Hu, Zhang, Zhou, Sun, Yang: "Doxycycline directly targets PAR1 to suppress tumor progression." in: Oncotarget, Vol. 8, Issue 10, pp. 16829-16842, (2017) (PubMed).

  • 抗原
    PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))
    别名
    F2R (F2R 产品)
    别名
    CF2R antibody, HTR antibody, PAR-1 antibody, PAR1 antibody, TR antibody, Par1 antibody, TRGPC antibody, AI482343 antibody, Cf2r antibody, ThrR antibody, Par-1 antibody, f2r-a antibody, par1 antibody, coagulation factor II thrombin receptor antibody, coagulation factor II (thrombin) receptor antibody, coagulation factor 2 (thrombin) receptor L homeolog antibody, F2R antibody, F2r antibody, f2r.L antibody
    背景

    Description: High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.

    Gene: F2R

    分子量
    48kDa
    基因ID
    2149
    UniProt
    P25116
    途径
    Nuclear Receptor Transcription Pathway, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus
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