PAR1 抗体 (N-Term)
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- 抗原 See all PAR1 (F2R) 抗体
- PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))
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抗原表位
- N-Term
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PAR1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
- 特异性
- Thrombin Receptor Antibody detects endogenous levels of total Thrombin Receptor.
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human Thrombin Receptor, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product F2R Primary Antibody
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- 应用备注
- WB: 1:500-1:3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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Inhibiting trophoblast PAR-1 overexpression suppresses sFlt-1-induced anti-angiogenesis and abnormal vascular remodeling: a possible therapeutic approach for preeclampsia." in: Molecular human reproduction, Vol. 24, Issue 3, pp. 158-169, (2018) (PubMed).
: "Doxycycline directly targets PAR1 to suppress tumor progression." in: Oncotarget, Vol. 8, Issue 10, pp. 16829-16842, (2017) (PubMed).
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Inhibiting trophoblast PAR-1 overexpression suppresses sFlt-1-induced anti-angiogenesis and abnormal vascular remodeling: a possible therapeutic approach for preeclampsia." in: Molecular human reproduction, Vol. 24, Issue 3, pp. 158-169, (2018) (PubMed).
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- 抗原
- PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))
- 别名
- F2R (F2R 产品)
- 别名
- CF2R antibody, HTR antibody, PAR-1 antibody, PAR1 antibody, TR antibody, Par1 antibody, TRGPC antibody, AI482343 antibody, Cf2r antibody, ThrR antibody, Par-1 antibody, f2r-a antibody, par1 antibody, coagulation factor II thrombin receptor antibody, coagulation factor II (thrombin) receptor antibody, coagulation factor 2 (thrombin) receptor L homeolog antibody, F2R antibody, F2r antibody, f2r.L antibody
- 背景
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Description: High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.
Gene: F2R
- 分子量
- 48kDa
- 基因ID
- 2149
- UniProt
- P25116
- 途径
- Nuclear Receptor Transcription Pathway, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus
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