电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

THRAP3 抗体 (N-Term)

THRAP3 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6265560
发货至: 中国
  • 抗原 See all THRAP3 抗体
    THRAP3 (Thyroid Hormone Receptor Associated Protein 3 (THRAP3))
    抗原表位
    • 15
    • 13
    • 9
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 50
    • 29
    • 16
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    人, 大鼠, 小鼠
    宿主
    • 50
    克隆类型
    • 50
    多克隆
    标记
    • 18
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This THRAP3 antibody is un-conjugated
    应用范围
    • 39
    • 16
    • 13
    • 13
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    THRAP3 Antibody detects endogenous levels of total THRAP3.
    预测反应
    Bovine,Sheep,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human THRAP3, corresponding to a region within N-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product THRAP3 Primary Antibody
  • 应用备注
    WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    THRAP3 (Thyroid Hormone Receptor Associated Protein 3 (THRAP3))
    别名
    THRAP3 (THRAP3 产品)
    别名
    TRAP150 antibody, 9330151F09Rik antibody, B230333E16Rik antibody, Trap150 antibody, trap150 antibody, Thrap3 antibody, MGC132228 antibody, zgc:85716 antibody, thyroid hormone receptor associated protein 3 antibody, DNA cross-link repair 1A protein antibody, thyroid hormone receptor associated protein 3 S homeolog antibody, thyroid hormone receptor-associated protein 3 antibody, thyroid hormone receptor associated protein 3b antibody, THRAP3 antibody, CpipJ_CPIJ018886 antibody, CpipJ_CPIJ019503 antibody, Thrap3 antibody, thrap3 antibody, thrap3.S antibody, thrap3b antibody
    背景

    Description: Involved in pre-mRNA splicing. Remains associated with spliced mRNA after splicing which probably involves interactions with the exon junction complex (EJC). Can trigger mRNA decay which seems to be independent of nonsense-mediated decay involving premature stop codons (PTC) recognition. May be involved in nuclear mRNA decay. Involved in regulation of signal-induced alternative splicing. During splicing of PTPRC/CD45 is proposed to sequester phosphorylated SFPQ from PTPRC/CD45 pre-mRNA in resting T-cells. Involved in cyclin-D1/CCND1 mRNA stability probably by acting as component of the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA. Involved in response to DNA damage. Is excluced from DNA damage sites in a manner that parallels transcription inhibition, the function may involve the SNARP complex. Initially thought to play a role in transcriptional coactivation through its association with the TRAP complex, however, it is not regarded as a stable Mediator complex subunit. Cooperatively with HELZ2, enhances the transcriptional activation mediated by PPARG, maybe through the stabilization of the PPARG binding to DNA in presence of ligand. May play a role in the terminal stage of adipocyte differentiation. Plays a role in the positive regulation of the circadian clock. Acts as a coactivator of the CLOCK-ARNTL/BMAL1 heterodimer and promotes its transcriptional activator activity and binding to circadian target genes (PubMed:24043798).

    Gene: THRAP3

    分子量
    109kDa
    基因ID
    9967
    UniProt
    Q9Y2W1
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway
You are here:
客服