TFCP2L1 抗体 (N-Term)
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- 抗原 See all TFCP2L1 抗体
- TFCP2L1 (Transcription Factor CP2-Like 1 (TFCP2L1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TFCP2L1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 特异性
- TF2L1 Antibody detects endogenous levels of total TF2L1.
- 预测反应
- Pig,Bovine,Sheep,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human TF2L1, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product TFCP2L1 Primary Antibody
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- 应用备注
- WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- TFCP2L1 (Transcription Factor CP2-Like 1 (TFCP2L1))
- 别名
- TFCP2L1 (TFCP2L1 产品)
- 别名
- CRTR1 antibody, LBP-9 antibody, LBP9 antibody, 1810030F05Rik antibody, 4932442M07Rik antibody, AA575098 antibody, Cp2l1 antibody, Crtr-1 antibody, D930018N21Rik antibody, Tcfcp2l1 antibody, zgc:91796 antibody, TFCP2L1 antibody, lbp-9 antibody, crtr1 antibody, lbp9 antibody, tfcp2l1 antibody, tfcp2l1a antibody, transcription factor CP2 like 1 antibody, transcription factor CP2-like protein 1 antibody, transcription factor CP2-like 1 antibody, transcription factor CP2-like 1 L homeolog antibody, TFCP2L1 antibody, LOC100078599 antibody, Tfcp2l1 antibody, tfcp2l1 antibody, tfcp2l1.L antibody
- 背景
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Description: Transcription factor that facilitates establishment and maintenance of pluripotency in embryonic stem cells (ESCs) (PubMed:25215486, PubMed:26906118). With KLF2, acts as the major effector of self-renewal that mediates induction of pluripotency downstream of LIF/STAT3 and Wnt/beta-catenin signaling (By similarity). Required for normal duct development in the salivary gland and kidney (By similarity). Coordinates the development of the kidney collecting ducts intercalated (IC) and principal (PC) cells, which regulate acid-base and salt-water homeostasis, respectively (By similarity). Regulates the expression of IC genes including subunits B1 and D2 of the V-ATPase complex, OXGR1, CA12, SLC4A1, AQP6 and IC-specific transcription factor FOXI1 (By similarity). Regulates also the expression of JAG1 and subsequent notch signaling in the collecting duct (By similarity). JAG1 initiates notch signaling in PCs but inhibits notch signaling in ICs (By similarity). Acts as a transcriptional suppressor that may suppress UBP1-mediated transcriptional activation (By similarity). Modulates the placental expression of CYP11A1 (PubMed:10644752).
Gene: TFCP2L1
- 分子量
- 55 kDa
- 基因ID
- 29842
- UniProt
- Q9NZI6
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