TCOF1 抗体 (N-Term)
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- 抗原 See all TCOF1 抗体
- TCOF1 (Treacher Collins-Franceschetti Syndrome 1 (TCOF1))
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抗原表位
- N-Term
- 适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TCOF1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- TCOF1 Antibody detects endogenous levels of total TCOF1.
- 预测反应
- Pig,Bovine,Horse,Sheep,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human TCOF1, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product TCOF1 Primary Antibody
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- TCOF1 (Treacher Collins-Franceschetti Syndrome 1 (TCOF1))
- 别名
- TCOF1 (TCOF1 产品)
- 别名
- TCOF1 antibody, AA408847 antibody, AW209012 antibody, treacle antibody, MFD1 antibody, TCS1 antibody, treacle ribosome biogenesis factor 1 antibody, Tcof1 antibody, TCOF1 antibody
- 背景
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Description: Nucleolar protein that acts as a regulator of RNA polymerase I by connecting RNA polymerase I with enzymes responsible for ribosomal processing and modification (PubMed:12777385, PubMed:26399832). Required for neural crest specification: following monoubiquitination by the BCR(KBTBD8) complex, associates with NOLC1 and acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification (PubMed:26399832).
Gene: TCOF1
- 分子量
- 152kDa
- 基因ID
- 6949
- UniProt
- Q13428
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