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TBC1D23 抗体 (Internal Region)

TBC1D23 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6265479
发货至: 中国
  • 抗原 See all TBC1D23 products
    TBC1D23 (TBC1 Domain Family, Member 23 (TBC1D23))
    抗原表位
    • 4
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 9
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 9
    克隆类型
    • 9
    多克隆
    标记
    • 6
    • 1
    • 1
    • 1
    This TBC1D23 antibody is un-conjugated
    应用范围
    Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    特异性
    TBC1D23 Antibody detects endogenous levels of total TBC1D23.
    预测反应
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human TBC1D23, corresponding to a region within the internal amino acids.
    亚型
    IgG
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    TBC1D23 (TBC1 Domain Family, Member 23 (TBC1D23))
    别名
    TBC1D23 (TBC1D23 产品)
    别名
    RGD1307925 antibody, NS4ATP1 antibody, 4930451A13Rik antibody, AU015720 antibody, AU043671 antibody, AU043778 antibody, D030022P07Rik antibody, W51689 antibody, zgc:63756 antibody, TBC1 domain family, member 23 antibody, TBC1 domain family member 23 antibody, Tbc1d23 antibody, TBC1D23 antibody, tbc1d23 antibody
    背景

    Description: Putative Rab GTPase-activating protein which plays a role in vesicular trafficking (PubMed:28823707). Involved in endosome-to-Golgi trafficking. Acts as a bridging protein by binding simultaneously to golgins, including GOLGA1 and GOLGA4, located at the trans-Golgi, and to the WASH complex, located on endosome-derived vesicles (PubMed:29084197). Plays a role in brain development, including in cortical neuron positioning (By similarity). May also be important for neurite outgrowth, possibly through its involvement in membrane trafficking and cargo delivery, 2 processes that are essential for axonal and dendritic growth (By similarity). May act as a general inhibitor of innate immunity signaling, strongly inhibiting multiple TLR and dectin/CLEC7A-signaling pathways. Does not alter initial activation events, but instead affects maintenance of inflammatory gene expression several hours after bacterial lipopolysaccharide (LPS) challenge (By similarity).

    Gene: TBC1D23

    分子量
    78 kDa
    基因ID
    55773
    UniProt
    Q9NUY8
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