SYNPO2 抗体 (Internal Region)
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- 抗原 See all SYNPO2 抗体
- SYNPO2 (Synaptopodin 2 (SYNPO2))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SYNPO2 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Western Blotting (WB)
- 特异性
- Synaptopodin Antibody detects endogenous levels of total Synaptopodin.
- 预测反应
- Bovine,Horse
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human Synaptopodin, corresponding to a region within the internal amino acids.
- 亚型
- IgG
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- SYNPO2 (Synaptopodin 2 (SYNPO2))
- 别名
- SYNPO2 (SYNPO2 产品)
- 别名
- SYNOP2 antibody, RGD1564779 antibody, 1110069I04Rik antibody, 2310068J10Rik antibody, 9530006G20Rik antibody, AI848603 antibody, Myo antibody, synaptopodin 2 antibody, synaptopodin-2 antibody, SYNPO2 antibody, LOC100484043 antibody, Synpo2 antibody
- 背景
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Description: Has an actin-binding and actin-bundling activity. Can induce the formation of F-actin networks in an isoform-specific manner (PubMed:24005909, PubMed:23225103). At the sarcomeric Z lines is proposed to act as adapter protein that links nascent myofibers to the sarcolemma via ZYX and may play a role in early assembly and stabilization of the Z lines. Involved in autophagosome formation. May play a role in chaperone-assisted selective autophagy (CASA) involved in Z lines maintenance in striated muscle under mechanical tension, may link the client-processing CASA chaperone machinery to a membrane-tethering and fusion complex providing autophagosome membranes (By similarity). Involved in regulation of cell migration (PubMed:22915763, PubMed:25883213). May be a tumor suppressor (PubMed:16885336).
Gene: SYNPO2
- 分子量
- 99-115 kDa
- 基因ID
- 171024
- UniProt
- Q9UMS6
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