STAMBP 抗体 (C-Term)
-
- 抗原 See all STAMBP 抗体
- STAMBP (STAM Binding Protein (STAMBP))
-
抗原表位
- C-Term
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This STAMBP antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA
- 特异性
- STAMBP Antibody detects endogenous levels of total STAMBP.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human STAMBP, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product STAMBP Primary Antibody
-
-
- 应用备注
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
-
- 抗原
- STAMBP (STAM Binding Protein (STAMBP))
- 别名
- STAMBP (STAMBP 产品)
- 别名
- AMSH antibody, 5330424L14Rik antibody, 5730422L11Rik antibody, AW107289 antibody, Amsh antibody, mKIAA4198 antibody, stambp antibody, zgc:66147 antibody, STAM binding protein antibody, Stam binding protein antibody, STAM binding protein a antibody, STAMBP antibody, Stambp antibody, stambpa antibody
- 背景
-
Description: Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains (By similarity). Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF. Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7. Has a key role in regulation of cell surface receptor-mediated endocytosis and ubiquitin-dependent sorting of receptors to lysosomes. Endosomal localization of STAMBP is required for efficient EGFR degradation but not for its internalization (By similarity). Involved in the negative regulation of PI3K-AKT-mTOR and RAS-MAP signaling pathways.
Gene: STAMBP
- 分子量
- 50 kDa
- 基因ID
- 10617
- UniProt
- O95630
-