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STAMBP 抗体 (C-Term)

STAMBP 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6265307
发货至: 中国
  • 抗原 See all STAMBP 抗体
    STAMBP (STAM Binding Protein (STAMBP))
    抗原表位
    • 15
    • 10
    • 8
    • 8
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 44
    • 30
    • 19
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 56
    • 4
    克隆类型
    • 57
    • 3
    多克隆
    标记
    • 24
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This STAMBP antibody is un-conjugated
    应用范围
    • 35
    • 22
    • 19
    • 13
    • 13
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    特异性
    STAMBP Antibody detects endogenous levels of total STAMBP.
    预测反应
    Pig,Bovine,Horse,Sheep,Rabbit,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human STAMBP, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product STAMBP Primary Antibody
  • 应用备注
    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    STAMBP (STAM Binding Protein (STAMBP))
    别名
    STAMBP (STAMBP 产品)
    别名
    AMSH antibody, 5330424L14Rik antibody, 5730422L11Rik antibody, AW107289 antibody, Amsh antibody, mKIAA4198 antibody, stambp antibody, zgc:66147 antibody, STAM binding protein antibody, Stam binding protein antibody, STAM binding protein a antibody, STAMBP antibody, Stambp antibody, stambpa antibody
    背景

    Description: Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains (By similarity). Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF. Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7. Has a key role in regulation of cell surface receptor-mediated endocytosis and ubiquitin-dependent sorting of receptors to lysosomes. Endosomal localization of STAMBP is required for efficient EGFR degradation but not for its internalization (By similarity). Involved in the negative regulation of PI3K-AKT-mTOR and RAS-MAP signaling pathways.

    Gene: STAMBP

    分子量
    50 kDa
    基因ID
    10617
    UniProt
    O95630
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